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Could be useful if you wrote your neural net with Applescript, I guess.

I agree. Once we passed the 640k mark it all became an excuse for lazy tool development.

Or if you use sap Hana, or Microsoft SQL server, or R, or Oracle, or anything that you pay "per instance" licensing on.

There are many applications where a single addressable memory space are still required/preferred.

Look into "tidalscale" if you want too see the logical extension for this.