I see, this really threw me off:

"Rsync over HTTP — zsync provides transfers that are nearly as efficient as rsync -z or cvsup, without the need to run a special server application. All that is needed is an HTTP/1.1-compliant web server. So it works through firewalls and on shared hosting accounts, and gives less security worries."

The other child comment also touches on something that I seem to have skipped over, the .zsync metadata file which contains pre-calculated rsync hashes. Using this means software isn't needed, but during upload the file needs to be processed to produce this metadata.