> I would expect that the social stigma would severely limit uptake in school though, which is why this isn't standard today -- kids can be rather vicious when they pick up on any hint of difference or weakness.

Random idea--what about a completely opaque contact lens, with an image of an iris/pupil on the outside, customized for the person's eye color? It would likely be noticeable up close, but could take away a lot of this social stigma.