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Just because there aren't studies on something does not mean it is not true. Science lags, and citizen scientists are left to explore and confer with each other to find what works and what does not. It is ignorant to ignore and belittle the progress in many fields that occurs before it is formally verified.

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It's not just the lack of studies, although that doesn't help. Why don't amateur "psychonauts" just do these blind tests themselves? Clearly they have enough product to do it, but they won't. Gwern is pretty much the only one who bothered, and his results were negative.

I'm not ignoring and belittling the progress because of the lack of formal verification. I'm belittling it because even amateurs refuse to take the first step towards confirmation of effects.

A classic research paper illustrating your point:

http://www.bmj.com/content/327/7429/1459

Love this study, thanks for reminding me that there are no randomised controlled trials of people using parachutes when they jump out of planes. I guess everyone should stop using parachutes then...

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