Last time I took the Megabus, the bus drivers were complaining that the company had sold the Midwest division (or something like that) to Coach USA. Indeed, the last few times I took it from Chicago to Ohio, they were Coach USA buses instead of the usual blue double-decker Megabuses. Apparently they downsized majorly in the region [1].
It didn't strike me as a particularly profitable venture in this country.
[1] http://www.chicagotribune.com/business/ct-megabus-downsizing...