Sitting will kill you. I managed to drop 60 lbs (205 to 145 at 5’8”) but without excercise, and I mean _real_ regular cardio and resistance training, I’m a thin but unfit person.
The open office craze and being on call all the time might have affected my sanity, seriously.
Any employer that demands more than 45 hours a week, unreasonable on call demands, and isn’t willing to let you take 1-2 breaks per hour isn’t worth pursuing.