I found OpenVPN to just feel VERY VERY clunky. The clients look ugly and unpolished. Before anyone says that's superficial, I do think it shows a lack of attention to detail. Setting up the server also wasn't terribly easy (it wasn't too hard either for someone like me who's used Linux for many years).
I think most of OpenVPN's value has come from the fact that it's the last difficult of solutions to implement.
For the record, I wasn't claiming that WireGuard was this easy to setup. But I think the mentality of WireGuard is simplicity. I think it's only a matter of time before someone DOES implement a single click client/server with it.
Right now I use Algo, which is just an excellent set of scripts used to setup VPN servers. This way I don't have to use OpenVPN, and I can actually use IPSec with built-in OS clients.
Update: Also I'd like to add that WireGuard just feels like the kind of thing Apple would've implemented in their OS 10 years ago. But Apple today wouldn't. They just seem to be barely treading water in their MacOS group.