Is that a real world scenario or something you can imagine but haven't actually done?
Polymer starter kit
https://github.com/Polymer/polymer-starter-kit
- npm
- bower
- polymer-cli
Doing a polymer test requires downloading and installing Web Component Tester, which then requires:
- npm
- grunt
- gulp
- bower
My relatively standard project (using React) needs just Yarn and Webpack. It's got quite some dependencies, but I've never run into those being insufficient.