I live in Flatiron. My neighbourhood has multiple experimental ballet, jazz, classical music and small-style theatre venues. And it isn’t even a hotbed for any of those things!
For the audience it comes with, New York is cheap. Add to that our strong subsidised housing programs, many of which have special vouchers for artists, and our comfort with roommates and lack of a need for a car and I think you’ll find a thriving creative scene, in Manhattan and across New York.