What made it so previously unthinkable?
Admitting you have invested twenty years of research and you're not an inch closer- in fact you went down the wrong path entirely- would be a pretty bitter pill to swallow, both for researchers and patients.
Admitting you have invested twenty years of research and you're not an inch closer- in fact you went down the wrong path entirely- would be a pretty bitter pill to swallow, both for researchers and patients.
I'm fairly certain I understand the brain well enough to know our understanding of the brain is rudimentary and there is no reason to become attached to a vague preliminary model like this "amyloid hypothesis".