I haven't tested myself (I'm just one dude - there's a lot I'd like to do but haven't yet), but I see no reason why it wouldn't work well. I try to design semantically and everything is rendered server-side.
But, in reality, I don't think this is the kind of website that would be usable for a blind person anyway. There's not really anything to read. There would be much better ways for a blind person to get information than using this website.