I think, the scaffold is an extremely important part of the process, it has chemical and physical signals which allow stem cells to develop properly. I haven’t heard of a plastic scaffold being used except in Macchiarini scandal, where the patients either died or had to have their artificial windpipe replaced. And that was for a windpipe which is a layered 2D structure, not something like a lung with an enormously complicated 3D vasculature. I suspect artificial scaffolds will be far more difficult than the process covered here.