I originally wrote it to analyze large data sets (where "large" meant 16+ GB which was much larger than the commonly available RAM at the time).
It integrated nicely with OCaml. You could create ordinary OCaml objects then incrementally "mark" them so those objects would be moved (recursively) into the ancient heap. The objects could still be accessed as if they were ordinary OCaml objects even if they were on the ancient heap. On the other side you could mmap a previous heap and access the objects as if they were regular OCaml objects directly (with a few shortcomings - see README). Depending on your access pattern this worked well even if available RAM was much smaller than the size of the data set.
[1] http://git.annexia.org/?p=ocaml-ancient.git;a=blob;f=README....