Seriously? Best cartoon drawing on the web? I doubt that :)

I used to do all the artwork in ink and then scan it. Now I do it all on my iPad with SketchBook Pro (took me a while to figure out how to get decent quality this way- At first, I didn't think decent drawing on an iPad was possible)

The animation was all done by importing bitmap artwork into Toon Boom animation. It's a cheesy Windows program (i.e. save your work every 30 minutes, or else...) but is feature rich.