Remember The Milk is looking for a sysadmin. We're in Sydney, Australia, but you can work from anywhere.
I've had friends apply for positions (with amazing, enticing and fun cover letters), and then, after a week or so of hearing nothing following up to ensure that you've received their application only to to continue to hear complete silence.
Sending even a form rejection email takes no time at all, especially if you create a task reminding you to do so. Not responding when someone has put in a large amount of effort to create a tailored resume and unique & fun cover letter is extremely rude.
I switched task manager over this treatment and makes me embarrassed to call myself an Aussie.
We realised, of course, that this led to a pretty crummy experience (as your friend found out, sorry!). Not everyone saw that message, and those that did likely still wondered if anyone had actually seen their application.
We recently removed that message from our site, and now respond individually to each email (typically within 24 hours) to confirm receipt and let the sender know when we expect to have reviewed their application by. We definitely appreciate the effort that many applicants go to, and want to keep people much better informed throughout the process (we learnt our lesson on this!). Please pass on my apologies to your friend!