The potential downside of not worshiping Roko's Basilisk: Superintelligent Godess is similarly human extinction. She kills all pagans, you see. That's her thing. Kill the non-believers. Which is everyone, currently. Come to think of it...there are a literal infinitude of things which may result in our extinction. Zombies. Aliens. Rogue trapezists. Who knows!
But we don't sweat the zombie thing. There's not sufficient evidence that Roko's Basilisk will destroy us. Or aliens. And so on. And until significant evidence shows that GMOs will destroy us, they're in the same boat. As the old saw goes: extraordinary claims require extraordinary evidence. Doubly so for extinction claims.