I carry around anxiety medication prescribed by my doc, but... just the effect of having something that someone tells me will prevent an all out panic is enough that I've never actually needed to take one. The magic isn't powerful enough to make the core problem go away, but it is pretty good at giving me another tool to control it.
No doubt other people are having the same realizations, CBD capsule prices have gone through the roof.
But I suspect that there might be other factors here that might influence your study design. Mostly because neurotransmitters are super complicated.