Besides, isn't discussion of brains and consciousness perfectly relevant in the context of QM, given the requirement for rigorous definitions of observation, observers, etc.?
But most people want to know why, if the universe is quantum, does it present such a convincing illusion of being classical.
You can still ask if there are other methods that convey understanding about reality than this method, but it's not in the purview of physics.
With respect to Many-Worlds, it is better understood as a formal problem. It stands in opposition to a formulation of quantum mechanics that cannot be used to model the universe as a system because what constitutes measurement was not described by that formulation, but measurements affected the system.