My own experience, since we're swapping anecdotes and beyond confirming that stuff exists, is that the people I've kept in touch with from that world aren't like that, whether they went to Peru once, or a dozen times, or never. They have reliably grown in ways they can't imagine themselves having done, without their work with the medicine. Since you can't A/B test someone's life, you can never say, but having seen however much of these people's lives, they all seem better off, in so many ways.
But selection bias is a thing, obviously. And dueling anecdata is interesting. Just probably not very useful.
EDIT: Phrasing
The 30+ crowd in Ayahuasca/Psychedelics have been some of the kindest, most giving people I have ever met in my life.