A lot of people talking about how hard it would be for him to kill himself and conspiracy stuff, but if there is a conspiracy then I think it's just as likely that Epstein could use his immense resources and connections to make sure that someone was looking the other way when he attempted.
It certainly could be a murder, but I'm not quite as convinced as other people seem... I'm sure it's very convenient for lots of his ghoulish friends, but it also makes a lot of sense that he would do anything necessary to get out of facing his crimes and the surrounding media circus.