Work is currently being done on the LANPR branch as part of the GSoC. This branch is meant to replace the Freestyle system which is currently used for line rendering. [0]
Otherwise we already have the "Shader to RGB" node which is extremely useful to create NPR shaders.
There's also an add-on which can be used to deform a mesh based on greasepencil strokes, I assume 2D animators would love this. [1]
If you're interested in blender NPR news I highly recommend following the BNPR Show on youtube. [2]
[0]: https://wiki.blender.org/wiki/User:Yiming/GSoC2019/Updates
[1]: https://www.youtube.com/watch?v=w3nmEjum8kg
[2]: https://www.youtube.com/watch?v=38ETYyzrTzM&list=PLSMetEtY22...