Large aircraft are basically self-driving these days. Pilots can choose to do almost nothing at all from takoff to landing. However, the failure modes are all mostly catastrophic so pilots remain under the assumption that they can slightly increase the survivability rate when the automation fails. Modern drone systems are also have elements of this kind of automation and can fly complex flight paths and station keep and land and so on more or less on their own.

Some large boat systems have are also similarly "self-driving" and can navigate to way points and along various lanes without too much intervention. They need pilots and tugs for the small-nav stuff like canals and ports and so on, there's simply too many permutations of "things that can be hit and sunk" to rely on the automation. Smaller boats can also buy commercial "autonav" systems that link the engine, steering and such to GPS. However, the marine environment is hellish on equipment.

Trucking is being seriously looked at, with active test runs, but like big ships needs local pilots for the end-points and local nav. Again too many things in flux and too many things to hit.

Cars exist basically continuously at the terminal ends of the trucking problem and are trying to solve the local pilot problem. Humans, with our highly adaptive sensory-response systems can do it to various levels of skill, but even we have lots and lots of failure modes even without impairment.