Doesn't the fact that the twin-engine planes have to submit to more stringent ETOPS requirements mean the FAA believes they're less reliable than four engine planes?
I could build a jet engine in my garage and the FAA wouldn't let me fly 270 minutes away from an airport with paying passengers on it just because I made four of them. Certification is always going to be important.
Why not research a thing BEFORE deciding you have a strong opinion about it?