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Side note: I’ve been self-experimenting with high doses of niacinamide, and experiencing some weird side effects, possibly immune-related, like angular chelitis. Probably unrelated.

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Might be inhibiting sirtuin activity... http://www.jbc.org/content/277/47/45099.short

Please tell us more.

High dose of NMN are supposed to be helping develop some cancers.

angular chelitis is totally new to me. Are you on retinoids by any chance?

I took a lot of cod liver oil once it started, maybe a little bit before too, so I suppose it could be that. I did a lot of research into what would increase NAD levels, and it’s all pretty inconclusive, so I figured niacinamide was as good as any other B3 in the pathway. I later found that it chelates with some minerals, so I may be giving myself a deficiency.

Yes a deficiency is far more likely than an autoimmune disorder

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