This is interesting, but no mention of how the hosts process these molecules. We all know that our body has problems processing artificial molecules (artificial sweeteners, etc).
https://www.amazon.com/Haribo-SUGAR-Classic-Gummi-Bears/prod...
And fwiw the whole point of "non-caloric" artificial sweeteners is that they're indigestible.
https://chriskresser.com/how-artificial-sweeteners-wreak-hav...