I've found that while it changes the constraints on what is fun, some fun is still possible, and the ability to preserve state across devices/locations sometimes offsets the 'loss of fun'
e.g. coding / light 'ops' stuff that is just 'graphical text' is fairly bearable to me in the ~100ms range with good compression/low bandwidth settings, since often you can blindly type some code/commands and take a breath while the UI updates. Video/Graphics/Etc or heavy GUI interactivity starts to get a bit painful.
one clear benefit to cloud is faster in-cloud bandwidth/latency which could make up for the less responsive UI depending on your use case