I've never tried to compile to WASM. It really depends on how much of the OS APIs need to be fixed. e.g., I don't think WASM supports memory maps as one example. In that case, ripgrep could be made to compile without support for memory maps with a bit of work. But that's an easy case. What other things does WASM not support? What about typical file/directory APIs? I don't think it does, or it least, it looks like Rust's standard library doesn't implement anything for them:
https://github.com/rust-lang/rust/blob/master/src/libstd/sys...At that point, it would be hopelessly difficult to build ripgrep. The right path then would be to build a new application that uses whatever of ripgrep's libraries make sense.
Popping up a level though, why would you want to compile to WASM? If you're using Node, then surely you can build an FFI bridge to Rust's regex library. At least at that point, you'd be using the same regex engine. I even maintain official C bindings for them: https://github.com/rust-lang/regex/tree/master/regex-capi
EDIT: Oh, and not sure if this is useful, but the regex crate itself should compile to WASM just fine. I know I've seen people run it in the browser before. If there's a problem here, then please file a bug!