Don't Crohn's and IBS nigh disappear when using CBD heavy Cannabis? Pointing towards a combination of inflammation and stress.
Disease modifiers like methotrexate or stelara will suppress aspects of the immune system, which protects the body from further damage. Ibuprofen on the other hand will mask pain but not modify the underlying issue.
If CBD was effective (for me it doesn't seem to be), then the challenge is in understanding if it is modifying the disease, or just hiding symptoms like ibuprofen would for pain.