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So, an already slow language made slower?

No thanks.

The main point though, is that running Python in the browser it's an unnecessary abstraction because you get a crappier version of something that runs pretty well natively. If you're starting from scratch, I think that the browser might be close to native performance in some tasks. Porting existing applications is a pain when you start looking into the details.

The problem is not so much the run-time performance of the code, it's the overhead of loading the Python run-time environment over the network the first time you open the page.