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Comment by raducu | Hacker News Reader

If you used to be on SSRIs and they worked, then LSD doesn't sound like a good match.

I regret not taking psychedelics, but I hallucinated from a large dosage of hashish and had visual disturbances for a couple of days after, so I figured it's better to not mess with other psychedelics.

I also got a bad panic attack from a moderate dosage of stimulants(bad idea mixing them) and I could not drink coffee for 2 years, or I would get a panic attack just from the coffee -- it all went away eventually and I can drink coffee without a panick attack now (though it does seem to cause joint pain so I try to avoid it).

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>If you used to be on SSRIs and they worked, then LSD doesn't sound like a good match.

Well honestly I had thought that LSD could be great for anxiety and depression under the right set and setting. Since I was very sure I could have a great setting (which I could) I thought that my chances of a bad trip were very minimal. Unfortunately I think I just didn't pay enough attention to the "set" part

> If you used to be on SSRIs and they worked, then LSD doesn't sound like a good match

Do you have any evidence at all to support this claim?

LSD isn't inherently an anti-depressant. The research around psychedelics involves many sessions of intense therapy with LSD used in some sessions to help facilitate the therapy.

Researchers aren't just dosing people with psychedelics and walking away. The drug itself isn't doing the heavy lifting of addressing the problems.

I have absolutely no evidence, just my reasoning that if you are depressed and SSRIs work, there must be something wrong with those serotonin networks and SSRIs working mean some balance was restored; LSD will just blast the same networks.

I was not under the impression that OP did LSD in a therapeutical setting.

>though it does seem to cause joint pain

Wait, you get this, too? I have searched for answers to this and gotten nothing. I have long suspected that my coffee habits correspond to my joint pain, but I have associated it with many other things in a search for truth. Can you elaborate?

It is just an observation that I made, the research seems to be mixed.

My joint pain started a couple of years ago (early 30s), with really bad pain in my thumb joint after some exertion, X-ray or MRI showed I had some inflammation and excessive liquid, the pain went away after one month or so; then I got pain on the outside of my elbows (perhaps from incorrect posture and lifting my toddler all the time); I originally thought it had to do with my nicotine usage, but I quit for some good months and nothing happened, on the contrary, I started using more coffee and my pain got worse.

I don't think the coffee is 100% responsible, rather that it exacerbates some underlying condition; but so far it is pretty dramatic -- after quitting coffee for a couple of days, my pain is almost gone -- and that happened for too many times to be just a coincidence(though it could).

Mental disturbances from hashish and psychedelics, while similar symptoms, are completely different internally. I wouldn’t rule out psychedelics based on that experience.

It wasn't just "mental" as in anxiety -- those were visual disturbances -- tracers in bright led lights, bright spots in grill patterns (metal or my chess-pattern shirt). The experience just made me think I'm predisposed to HPPD so I thought to play it safe.

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