That chrome extension has quite a memory footprint and seems to slow everything down... Haven't debugged, but my browsing sessions have been a lot less laggy since I disabled it...
Ghostery doesn't have as many bells and whistles, but it does greatly minimize the main annoyances out there, and it doesn't slow anything down noticeably.
It might all be a moot point by this time, since Youtube has changed how they load in such a way that it stutters no matter what because it is so busy downloading absolutely every item on a page all at one time instead of prioritizing the video stream like it did about a decade ago (back when you could pause a video and it would download fully even while not yet playing, thus avoiding the bottlenecks altogether...).
Ironically that puts me back to pausing everything first just to give all the useless off-screen crap enough bandwidth to load without ruining the video experience.
No matter how much faster technology gets, they find a way to make it more and more sluggish every time.
Not recommended over uBO.
Since Youtube chokes anyway nowadays (I did manage to stave it off for a few years), I might as well go back to uBO.
(Disclaimer: I worked there at the time)
If uBO is really responsible for this, you should probably check the box "Ignore generic cosmetic filters" in "Filter lists" pane. For instance, this is the default in Firefox for Android, I consider it's best for less powerful devices.
But now it'll be hard to tell, because Youtube has changed the way it downloads stuff in the background without prioritizing the stream. uBO definitely blocked a whole lot more noise than Ghostery does.