I use a wired mouse on my desktop with 1000 polls/sec and latency of about 5 ms.

On my laptop (which is 9 years newer and has similar benchmark results) I use a wireless mouse which has 125 polls/sec and latency of 20 ms.

Yes, one can tell the difference. It is possible to buy low-latency wireless mice. Next time, I will.

Bluetooth is a trash fire. I was hoping wireless USB would take off, but that's dead now.