JIRA being slow and sluggish doesn't really have anything to do with configuration. It's a horrible tool to navigate UX-wise.
I think the problem with JIRA is they don't really have a sane default install, it really feels like a bag of parts and then you assemble it. Maybe 2 or 3 opinionated templates that take a process end to end would help people, that just want to get started and that stare into the configurable abyss of JIRA and go "nope just want a ticket system".