Evolution is dominated by genetic drift, not natural selection, most of our genomes are junk, and we are in fact not very optimally adapted to our environments
The microbiome affects the brain, the immune system and is involved in multiple psychiatric/behavioral conditions
The identical ancestors point (in short, everyone is a descendant of everyone who ever lived approx 7000 years ago)
Mosaicism and chimerism - it's not clear "who we are" and it's not even "our genes"
Cancer behaves as though it were a living being of its own, there's evidence it could be a form of regression to unicellular lifeforms, and what's more it does have a microbiome of its own