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"once you have a comprehensive human connectome, there is still the challenge of emulating it digitally"

What would you do if Christof Koch is right and consciousness can not be computed?

His hypothesis if I understand it correctly, consciousness is the core part of existence so you would need to bring hardware into the world that not only is able to simulate the whole reality but to exist in it. Like property of physical reality and composition. That dude is a physicist believing in one single Universe, which probably also applies to most neuroscientists.

I'm not completely alien to the thought that someday we will get a digital companion that would be able to build a simulation of you in silico, but that simulation wouldn't be you.

This foundation sounds like complete science fiction, MRI really? We already have destructive approach in some countries - it's called euthanasia.

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