Years ago Zynga asked me how would I design a vending machine for blind people which was annoying because I asked it immediately back and clearly they hadn't even thought about it themselves. But then I brought up Ian Bogost and it was a hard stop basically, lol.
edit: Is it health? Like health tracking / indication? Not all games require it but maybe in the right context this would be the most important. This is snarky but I think you could run with it (health being the most important "number").