CMake might be the best thing we have in C++, but god does that fact tell you what we have to work with. I've never delved far into CMake, but I regularly make two observations that make my shy away:

1) Every time some "guide" gets posted on the programming communities, there's people pointing out mistakes, deprecated functions or alternatives.

2) If you look at the CMakeLists.txt files of various popular libraries, they all look different. There's some commonality but much less than what you would desire from a more or less standard build system.