When we did a stock market game in high school, we weren't allowed to use penny stocks.

I was so excited to find stocks that were doubling or tripling daily, only to realize how worthless it'd be in real life.

If anyone out there is a trader that works with penny stocks, I'd love to hear your insight. Is it possible to "game the system" by working with just a few (10-100) shares, instead of large holdings?