UWP is still the future of Windows API, Reunion is only lifting it from the Windows kernel, and exposing the respective COM infrastructure on the Win32 side as well.
When I create applications for customers I don't select technologies that require me to place workarounds that might make them repent for having me there in first place.
Hence why as much as I like F#, it is never going to be an option for me, until it has a seat at the table of the official languages.
Apparently that isn't an issue in your case, so good luck with the endeavours.