In regards to the hardware wallets, I'd buy 2 Trezors and store them in separate locations, so that if something happens to one, then you can still quickly and easily access your coins with the other one. (If you don't do this, then if you lost your Trezor for some reason, you'd have to order another one and wait for it arrive before you could recover and access your crypto)
If you're going bitcoin-only, you should consider Coldcard, which is the hardware wallet the hardcore bitcoiners love [1].
Cobo Vault is fairly new on the scene but is also getting rave reviews [2].
If you're going multisig, you should buy hardware wallets from different vendors to guard against a flaw or security vulnerability from any one vendor. For example, Trezor has some issues recently [3].
[1] https://coldcardwallet.com
[2] https://cobo.com/hardware-wallet
[3] https://blog.kraken.com/post/3662/kraken-identifies-critical...
Coinbase and Gemini are both regulated and safe as well.