To me, it's just so odd that people don't seem to understand why we have an ISS. Is the main argument "We've already learned what's needed about life in space, and now we don't need a space station anymore"? That seems absurd.
This spoken-word work from 1970 conveys the sentiment well: https://www.youtube.com/watch?v=goh2x_G0ct4
I'm not the biggest fan of manned spaceflight, and I couldn't care less about the ISS in particular.
But how does "ethical calculus" tell you to care about killing the ISS, vs. say LIGO, or wasteful military spending, or the video game industry, or foie gras, or goldschlager, or TikTok or astronomy in general or the Xbox or selfie sticks or...
If I was dictator, I'd prefer missions like New Horizons, but I can't see what ethical calculation is involved, I'd just rather see pictures of far away stuff than pay taxes for a space station to go around in circles.