Idem. I developed quite a number of desktop apps in a professional environment using wxPython. I found easy to quickly prototype new ideas. Also, you have access to the rich python ecosystem that other solutions for producing desktop apps won't have.

I found the API to be usable although the event system is bit limited in my opinion.

I even chosen it to develop a commercial app in c++(https://seamuove.com) mainly because I knew the API. Bonus is that you can produce small single exe using static linking.

Overall thanks for the effort dear wx team!