Surely something being misconduct or not is independent of someone's intentions? All kinds of people do bad things with good intentions.
If a person does something wrong but is not aware that what they did is wrong, the general reaction is not to "accuse them of misconduct", but rather to explain to them what it is about their action that's wrong, after which (if they in fact have good intent) they will no longer do that action.
It's also worth noting that quite a lot of broad crimes are strict liability these days, especially in America. For example money laundering is a strict liability crime, along with more obvious ones like speeding.
Misconduct though is not normally a criminal law term anyway. More like a code of conduct for an organisation.