Just listened to a Revisionist History episode that called out the harms of over-consumption of linoleic acid. Apparently the shift away from animal and towards vegetable oils in the '70s and '80s caused a lot of adverse health effects because we now consume multiples of the amount of linoleic acid that we did in previous generations.

Podcast: https://blog.simonsays.ai/the-basement-tapes-with-malcolm-gl...

(Somewhat biased, but still a good summary of the research) article on linoleic acid: https://theecologist.org/2014/feb/24/linoleic-acid-overwhelm...