The confusion between between a zero and an O would only happen to a human. The software would always consider them fully separate characters, would never, for example, silently convert all the zeros to O's during a copy-paste operation.

Also, zero-O confusion can be remedied by simply choosing the right font. But by definition, different types of spaces all have to look exactly the same when rendered as text. To inspect and diagnose the problem, you have to switch to a different form of character representation, like hex or Unicode code points.