It's not disconnected from reality to consider some groups of people to have too much power and to conspire against the best interests of society at large for their own benefits. What is delusional is to link that to reptiles or illuminatis, when the people pulling the strings are the same ones we see smiling on TV: multinationals and their lobbyists, bosses unions (eg. MEDEF in France), political parties.
Some of these interest groups tend to be more secretive (eg. Bildeberg, Dîners du siècle) but they are comprised of well-known figures whose interests align, and there's certainly not a single group of people controlling the entire planet's fate. It just so happens the rich and powerful have strong incentives to unite in order to screw the rest of us.