Just about everything out there will have decent Scheme support. It's a lisp, and it's a well-defined lisp. Scheme being well-specified makes everything simple. (Even the SRFIs are well specified.)
Our deploys were via Jenkins, but through Chicken's egg system it wasn't exactly a complicated process.
I hear a lot about “repl-driven” development with Clojure and CL, but anytime I get experimental with it I find myself neck-deep in editor configuration, or simply wrestling with emacs keybindings.
Because load was a primary concern, we mostly used a test-driven cycle where we'd spin up the server and then attempt to DOS it for every change. Not something you want happening much on your dev machine.
However, for the simpler tests, if the test system hit a failure, it would then drop into a REPL (not on the production server). So it was sort of like a nicer debugger.
The test system was developed in-house, but if I remember, it was something like a 100 lines of code. That's one of the things that Scheme guides you towards - if you don't have a wheel, it's generally five minutes to make one.
I wouldn't generally bother fighting with emacs or configuration for anything. If you're fighting your tools, you're not being productive. Fine to do if you're not being paid, not so fine in a workplace. Keep things simple, and you'll do better than if you try and be clever. Rainbow braces and documentation lookup will get you 99% of the way to where you want to be.
That being said, one of our devs wrote their code with Wisp (SRFI-119), and had a git pre-commit hook that automatically rewrote it back to normal Scheme, and another hook in their editor to turn it into Wisp code when they opened a file. Nobody noticed for over a month.
Scheme makes it easy to write the way that you want to, using the tools that you like.
For others like me who are curious, here's what Wisp looks like:
Wisp (SRFI-119) Simpler, indentation-sensitive Scheme - https://srfi.schemers.org/srfi-119/srfi-119.html
Discovering this philosophical division was a bit surprising to me when I first started talking to Lispers outside of my CL bubble.
When I get more free time I'm definitely eager to jump back to Guile programming. But on my first test drive, I definitely had good experience with the repl driven approach. No matter how barebones of a setup it is, it's better than my past Haskell repl experience, where it almost felt like a tool you need to use no matter what.
In the past, I've got quite far with two simple functions:
(define (e) (system "vi test.scm")) (define (l) (load "test.scm"))
and just rinse and repeat using those.
Don't let tooling get in your way.