Or perhaps that's a strawman -- would we not have bothered with this discourse if the reported fraction of teens reporting suicidal ideation who cited Instagram were 2% instead of 6%? 1%?
Given how many and how much young people use Instagram, what fraction there would represent "no effect size", where you can't get away with insinuating that Instagram has any causal impact on mood compared to any other activity that kids could be doing? It's probably not 0, right?