I'm not quite sure I understand the question exactly, but let me give it a try.
So, first off, each pop has a /24, so like the seattle-1 pop which is near me has 157.240.3.X addresses; for me, whatsapp.net currently resolves to 157.240.3.54 in the seattle-1 pop. these addresses are used as unicast meaning they go to one place only, and they're dedicated for seattle-1 (until FB moves them around). But there are also anycast /24s, like 69.171.250.0/24, where 69.171.250.60 is a loadbalancer IP that does the same job as 157.240.3.54, but multiple PoPs advertise 69.171.250.0/24; it's served from seattle-1 for me, but probably something else for you unless you're nearby.
The DNS server IPs are also anycast, so if a PoP is healthy, it will BGP advertise the DNS server IPs (or at least some of them; if I ping {a-d}.ns.whatsapp.net, I see 4 different ping times, so I can tell seattle-1 is only advertising d.ns.whatsapp.net right now, and if I worked a little harder, I could probably figure out the other PoPs).
Ok, so then I think your question is, if my DNS request for whatsapp.net makes it to the seattle1 PoP, will it only respond with a seattle-1 IP? That's one way to do it, but it's not necessarily the best way. Since my DNS requests could make it to any PoP, sending back an answer that points at that PoP may not be the best place to send me.
Ideally, you want to send back an answer that is network local to the requester and also not a PoP that is overloaded. Every fancy DNS server does it a little different, but more or less you're integrating a bunch of information that links resolver IP to network location as well as capacity information and doing the best you can. Sometimes that would be sending users to anycast which should end up network local (but doesn't always), sometimes it's sending them to a specific pop you think is local, sometimes it's sending them to another pop because the usual best pop has some issue (overloaded on CPU, network congestion to the datacenters, network congestion on peering/transit, utility power issue, incoming weather event, fiber cut or upcoming fiber maintenance, etc).
But in short, different DNS requests will get different answers. If you've got a few minutes, run these commands to see the range of answers you could get for the same query:
host whatsapp.net # using your system resolver settings
host whatsapp.net a.ns.whatsapp.net # direct to authoritative A
host whatsapp.net b.ns.whatsapp.net # direct to B
host whatsapp.net 8.8.8.8 # google public DNS
host whatsapp.net 1.1.1.1 # cloudflare public DNS
host whatsapp.net 4.2.2.1 # level 3 not entirely public DNS
host whatsapp.net 208.67.222.222 # OpenDNS
host whatsapp.net 9.9.9.9 # Quad9
You should see a bunch of different addresses for the same service. FB hostnames do similar things of course.
Adding on, the BGP announcments for the unicast /24s of the PoPs didn't go down during yesterday's outage. If you had any of the pop specific IPs for whatsapp.net, you could still use http://whatsapp.net (or https://whatsapp.net ), because the configuration for that hostname is so simple, it's served from the PoPs without going to the datacenters (it just sets some HSTS headers and redirects to www.whatsapp.com, which perhaps despite appearances is a page that is served from the datacenters and so would not have worked during the outage).