React only re-renders a component if the state changes, the props change, or a parent component re-renders. In my app, I only have one component where I needed to break out of the vdom, and none of the parent tree ever re-rendered (except when navigating to a new page, which correctly tears down the component), so it was as simple as just one useRef to grab a reference and one useEffect to pass it to my other code after the component rendered.